6-chloro-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridine
6-chloro-3,3-dimethyl-1,2-dihydropyrrolo[3,2-b]pyridine
CAS: 1604818-09-8
Molecular Formula: C9H11ClN2
6-chloro-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridine - Names and Identifiers
6-chloro-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridine - Physico-chemical Properties
| Molecular Formula | C9H11ClN2 |
| Molar Mass | 182.65 |
| Density | 1.154±0.06 g/cm3(Predicted) |
| Boling Point | 267.3±40.0 °C(Predicted) |
| pKa | 4.96±0.40(Predicted) |
6-chloro-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridine - Introduction
6-choro-3, 3-dimethyl-1,2-dihydropyrrolo[3,2-b]pyridine is an organic compound with the chemical formula C10H11ClN and a molecular weight of 185.65g/mol.
Nature:
-Appearance: Colorless or yellow crystal
-Melting point: about 106-107°C
-Boiling point: about 271-275°C(760 mmHg)
-solubility: insoluble in water, soluble in ethanol, chloroform and other organic solvents
Use:
6-chloro-3,3-dimethyl-1,2-dihydropyrrolo[3,2-b]pyridine can be used as intermediates in chemical research and synthesis. It is widely used in many reactions in organic synthesis, such as oxidation reaction, ketone synthesis, heterocyclic synthesis, etc.
Preparation Method:
6-chloro-3,3-dimethyl-1,2-dihydropyrrolo[3,2-b]pyridine can be synthesized by a variety of methods. Common methods include the reaction of 3-amino -4, 5-dimethylpyrrolo [3,2-b]pyridine with phosphorus pentachloride in the presence of 1,3-dichloroacetone, or by the condensation of indolinone and 2-chloropropanone.
Safety Information:
There are few toxicological and safety studies on 6-chloro-3,3-dimethyl-1, 2-dihydrobrrolo [3,2-b]pyridine, so appropriate laboratory safety practices should be taken. General laboratory safety regulations should be followed when using or handling the compound, such as protective gloves, goggles, and laboratory ventilation. Avoid direct contact with skin and inhalation of dust or vapors. During storage and transportation, it should be isolated from other chemicals and avoid contact with oxidants and strong acids. More research data is needed to determine the specific toxicity and safety of this substance.
Nature:
-Appearance: Colorless or yellow crystal
-Melting point: about 106-107°C
-Boiling point: about 271-275°C(760 mmHg)
-solubility: insoluble in water, soluble in ethanol, chloroform and other organic solvents
Use:
6-chloro-3,3-dimethyl-1,2-dihydropyrrolo[3,2-b]pyridine can be used as intermediates in chemical research and synthesis. It is widely used in many reactions in organic synthesis, such as oxidation reaction, ketone synthesis, heterocyclic synthesis, etc.
Preparation Method:
6-chloro-3,3-dimethyl-1,2-dihydropyrrolo[3,2-b]pyridine can be synthesized by a variety of methods. Common methods include the reaction of 3-amino -4, 5-dimethylpyrrolo [3,2-b]pyridine with phosphorus pentachloride in the presence of 1,3-dichloroacetone, or by the condensation of indolinone and 2-chloropropanone.
Safety Information:
There are few toxicological and safety studies on 6-chloro-3,3-dimethyl-1, 2-dihydrobrrolo [3,2-b]pyridine, so appropriate laboratory safety practices should be taken. General laboratory safety regulations should be followed when using or handling the compound, such as protective gloves, goggles, and laboratory ventilation. Avoid direct contact with skin and inhalation of dust or vapors. During storage and transportation, it should be isolated from other chemicals and avoid contact with oxidants and strong acids. More research data is needed to determine the specific toxicity and safety of this substance.
Last Update：2024-04-10 22:29:15
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